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Professor Tor Ny publish article in Thrombosis and Haemostasis on Plasminogens role in cutaneous wound healing

In the paper, Sulniute et al. show that plasminogen is transported to the wound by inflammatory cells early during the healing process, where it potentiates inflammation and how lack of plasminogen leads to extensive fibrin and neutrophil depositions in the wounded area long after re-epithelialisation, indicating inefficient debridement and chronic inflammation.

Plasminogen is a critical regulator of cutaneous wound healing.

Sulniute R, Shen Y, Guo YZ, Fallah M, Ahlskog N, Ny L, Rakhimova O, Broden J, Boija H, Moghaddam A, Li J, Wilczynska M, Ny T.Thromb Haemost. 2016 May 2;115(5):1001-9. doi: 10.1160/TH15-08-0653. Epub 2016 Jan 21.